Abdala, technical name CIGB-66, is a Covid-19 vaccine.
Its scientific title is “Phase III, multicenter, randomized, double-blind, placebo-controlled clinical trial for the evaluation in adults of the efficacy, safety and immunogenicity of the vaccine candidate CIGB-66 against SARS-CoV-2. (COVID-19)”
Its Issuing authority and the primary sponsor is Center for Genetic Engineering and Biotechnology in Havana, Cuba (CIGB)
Center for Genetic Engineering and Biotechnology in Cuba developed this vaccine. The reason behind its name is the patriotic drama by Cuban independence hero Jose Marti.
What is the Vaccine’s Target?
What is the Vaccine Type?
What is the Route of Administration?
Via Intramuscular Route
Mechanism of Action
It is a protein subunit vaccine containing COVID-derived proteins that trigger an immune response. However, Scientists didn’t publish the clinical trial full results.
What are the phases of the Clinical research ?
In July 2020, CIGB-66 commenced phase I/II clinical trials.
The Phase III trial compares 3 doses of the vaccine administered at 0, 14 and 28 days against a placebo. With the primary outcome measuring the proportion of cases reported for each group 14 days after the third dose.
The first dose was administered on 22 March and by April 4. The 48,000 participants had received their first dose, and second doses started being administered from April 5.
Third doses have started being administered on 19 April and on May 1, 97% of the original participants had received their 3 doses, the others 3% were lost in the process.
What is the reported efficacy of Abdala Vaccine?
On June 22, official Cuban government sources announced that the results of an initial study by the Cuban Center for Genetic Engineering and Biotechnology. They found the vaccine, administered in 3 doses spaced 2 weeks apart, had a 92.28% efficacy rate at preventing COVID-19.
This measure of efficacy includes infection by the initial strain of SARS-Cov-2 as well as the mutant Alpha, Beta and Gamma strains.
More Information about Vaccination
What is Vaccination?
Vaccination is a simple, safe, and effective way of protecting people against harmful diseases, before they come into contact with them. It uses your body’s natural defenses to build immunity to viral and bacterial infections and makes your immune system produces more antibodies to face these antigens.
Vaccines make your immune system ready to create antibodies, just as it does when a certain disease attacks our body. However, because vaccines contain only killed or weakened forms of germs like viruses or bacteria, they do not cause the disease or put you at risk of its complications.
Route of Administration of Most vaccines are by an injection, but some are orally (by mouth) or sprayed into the nose.
Why is Vaccination Crucial?
To begin with, vaccination is a safe and effective way to prevent disease and save lives now more than ever. Today there are different vaccines available, produced by different companies to protect against coronavirus.
When we receive the vaccine, we aren’t just protecting ourselves, but also those around us. Some people like those who are seriously ill. They can’t get certain vaccines so they depend on the rest of us to get the vaccines in order to help reduce the spread of disease. This is also known as “Herd Immunity”
Therefore, during the COVID-19 pandemic, vaccination continues to be critically important. The pandemic has caused a decline in the number of children receiving routine immunizations, which could lead to an increase in illness and death from preventable diseases.